Pain Sufferers May Benefit From Combining Opioids and Marijuana

Pain Sufferers May Benefit From Combining Opioids and Marijuana

In a study of monkeys where cannabinoids with morphine were combined, there was not a significant increase in impulsivity or memory impairment.  These findings suggest that using opioids and marijuana together could offer a safe way to cut opioid dosage among patients suffering from pain, and may reduce their risk of opioid addiction.

“These data provide additional evidence supporting the notion that opioid-cannabinoid mixtures that are effective for treating pain do not have greater, and in some cases have less, adverse effects compared with larger doses of each drug alone,” said Vanessa Minervini, PhD, a postdoctoral fellow at the University of Texas Health Science Center at San Antonio.

This research will be presented at the American Society for Pharmacology and Experimental Therapeutics annual meeting April 6-9 in Orlando, Florida.

Previous studies have suggested the cannabinoids in marijuana enhance some of the pain-relieving effects of opioid drugs but do not enhance effects related to addiction and overdose. However, both drugs individually are known to impair cognition, leading to a concern that such side effects could be amplified if opioids and marijuana are used together. Researchers say the new study offers encouraging evidence this is not the case.

“The current opioid epidemic underscores the need for safe and effective pharmacotherapies for treating pain,” said Minervini. “Combining opioid receptor agonists with drugs that relieve pain through actions at non-opioid mechanisms (for example, cannabinoid receptors) could be a useful strategy for reducing the dose of opioid needed to achieve pain relief.”

The researchers gave several monkeys moderate doses of morphine and CP55940, a synthetic drug that mimics the activity of the tetrahydrocannabinol (THC) naturally found in marijuana. They assessed impulsivity and memory with tests involving touch screens and treats. The results showed each drug impeded performance and that giving the monkeys both drugs together had a lessened effect on performance than either drug alone.

While clinical trials need to be conducted to confirm whether these results translate to humans, monkeys tend to process drugs similarly to humans and are considered a good model for cognition.

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Whatever

Not everyone can take THC or pot. Not everyone gets high from their opioid medication. Not everyone mixes booze with opioids. People who need opioid medication for pain are dependent not addicted.

Who is it that comes up with all these outdated, redundant, useless ideas about how to get relief from pain? We should maybe smoke pot with our oxycodine? This is a new idea?. Would these same people suggest that I soak in the tub, put an icepak on, chant OM, play a guitar, get another pet, get a new hair do? “They” keep suggesting things that were suggested years ago as if its new stuff. And they get paid for it! Its like tossing an elephant a protein bar for the days meal. Hey you useless idea freaks out there, do you think we’re that dunb? We are all seeing through you doctors, shrinks, workers, and phonies. We KNOW who doesn’t care. We know who really cares and its not the ones with worn out ideas. Its the ones who against the black tide continue to give us our needed meds. And I primarily mean oxycodone or WHATEVER it is that helps us.

Rebecca Hollingsworth

Well Dr. Fusfield, I’m royally screwed because I have a severe allergic reaction to acetaminophen! We are all trying to figure out ways to combat this fabricated opiod crisis. As our government works at lightning speed (only in deterring opiod prescriptions) we cpp’s are left to pick up the pieces of our fragmented lives. We need national attention for our plight. I’ve personally spoken to my U.S. senator but to no avail. Just keep fighting everyone and stay focused. Prayers for all on this Easter holiday.

Robert Ivan

**Thank you Moderator for considering my post to publish**

Thank you Dr. William Fusfield for bringing insight to this discussion. As with you, THC has absolutely no effect reducing my pain, but after all, no two CNS’s are the same.

One thought that might make sense is considering how much precieved pain is actually caused by the mind. If you don’t believe that the last 3-4 years has not contributed to massive amounts of stress to chronic pain patients, you are kidding yourself. High levels of stress can strain or destroy your adrenals, ending in many cases an Auto -Immune response.

Maybe in some cases Marijuana works because it alleviates stress that could be interpretive by the body as pain. Remove the stress, get a good’s night sleep (whatever that feels like) and you will notice pain reduction.

Or do you believe the government is here to help. Then why is it still a schedule 1 drug without any medicinal properties, the same as Heroin.

Franklin Roosevelt was elected President in 1933 because of his promise to repial the Vollstead Act or Prohibition. Our country was in the midst of the Great Depression and too much tax money was being lost to gangsters like Al Capone or Joseph P. Kennedy. We needed the tax money.

Today conditions are quite similar to the 30’s, our GDP is way under the 22+ Trillion we have in deficit. Not to mention the $220 Trillion in unfunded liabilities.
With 2 decades under our belt in Afghanistan were 90% of all the world’s poppy production comes from…..well you do the math.

Meg Taylor

Until insurance starts paying for marijuana, I cannot afford it. It makes sense though.

About time.. too late for me… Dying but it might help others…

Researcher

It increases the effects of analgesia from opioids times 6, thereby killing more pain with a lesser dose, keeping tolerance down.
It also removes the nausea that can accompany morphine, increases appetite for those who are ill….but all this is really old news.
All CPP’s who have been sick/injured for any length of time should know this.
Cognition not being affected is nice, but who cares?
The suicide rate is soaring, there are far more important things since most people in need of morphine & cannabinoid’s aren’t driving.

DB Stewart

I use cannabis and it helps me tolerate pain.

I have successfully used combined opioid and marijuana therapy for years with my chronic pain patients. I have seen the vast majority of them be able to keep their opiate use down for longer periods without increasing the dosages, as is common when they are on opiates alone. They have also been able to avoid other combinations of medications like benzodiazepines, muscle relaxers, and such that contribute to many adverse events when used with opiates. It’s too bad that other providers, especially in the Douglas County area of Oregon, outright LIE to their patients and claim that the combined use of opiates and marijuana is ILLEGAL. There is NO law that prevents it. They just don’t want to do it and LIE to hide their personal biases and discrimination. Some of them will claim that they could lose their federal funding if they allowed such combined use. These little Community Health Clinics in Roseburg and such have thrived on federal and state funds to create large money-making organizations while providing little in pain management care. Long before the CDC Guidelines came out in 2016, they were forcefully tapering Oregon Health Plan (Medicaid) patients off opiates in 2013. It’s all about the money. Not paying for pain medications means bigger bonuses for the providers who refuse to write the prescriptions. They get paid by the count of patients assigned to their clinics, whether they see the patient or not. But when they have to provide care, they lose money, so anything they can deny as far as treatments or medications means they save money. They commonly DENY referrals to any provider out of town. They DENY imaging, surgeries, and so much more, all to ensure their bigger bonuses at the end of the year. For them the Oregon Health Plan has been a piggybank for their personal use. They hold closed door meetings when discussing the use of tax-payer dollars. Multiple bills in the legislature have failed to pass to change that due to lobbyist payouts.

Bill

Over the last year or so I began thinking that the majority of “Folks” who make Laws, Regulations, judgements and the like, have never even experienced Cannabis
I propose that an edible form of moderate strength cannabinoids, including THC be produced. Then, Congress can all have a Saturday-Sunday trial so at least they would have a clue to what they’re discriminating against.
This would also be a viable means of showing Pain Mgmt. Doctors, and others concerned what cannabis “feels like” and the rest .I wrote a High School Term Paper on the Legalization of marijuana in 1971, and I still advocate the benefits of cannabis. I’d Love to not have to try hiding it lest I lose My right to opiate pain meds. You know; “The pursuit of happiness”… not to mention the depths of manic-depressive illness.

Terri James

PS. I wish they would have also listed with their “findings” whether or not the monkeys that had medication administered to them, had severe chronic pain and in what parts of their bodies they were found. Did they have chronic back pain, bulging and degenerative discs, metal screws and rods in their bodies, suffer from EDS, cancer or fibromyalgia?! Were they using a wheelchair or cane? Also how many car or bike accidents they have been involved in, are they veterans and how long had they been suffering before allowing them there pain-relieving medication!

Robert

**In the earnest desire to help clarify this subject, I hope the moderator allows this to post. My intentions are only to help.**

I’ve posted statements about the possible dangerous effects when dealing with THC levels above the normal 10%-14% that kids in the 60’s may have smoked, but not inhaled (Clinton). Now we are freebasing Marijuana to 90% THC. Crack Mary Jane and they don’t even regulate it the same as cigarettes or alcohol? Wake Up!

In relation to the CNS, 27.5% of what I like to call the G – protein Super Highway, is made up of opioid and cannabinol receptors and they can be found in the same neighborhood.
Opiates are nature’s natural replacement, Endorphins and when the returning soldier (hypothetical) is injured by having a heavy sword cause not just cuts, but blunt force trauma, here comes the poppy plant to the rescue for pain.

Not altered to Heroin and no major problem even to those who are resistant (not because they’re tough, but they have body chemistry different from any other human on the planet) to addiction .

For the Marijuana plant, which by the way both are safe even if a ignorant animal decides to take a bit from the fruit, bud or pod, was meant for those suffering from PTSD while their mind had a chance to heal along with a medicine man to regulate and heal along the way. Marijuana allowed a mentally traumatized individual to heal, with the help of a care giver.

Both had a specific purpose and safe until man came along and “HELPED” out to be transformed into poison.

Whether or not you are a Physicians assistant or a Physician, please let’s accept the fact that the government lied, misrepresented, mis-remembered to us again. We may all (Including Pain Patients) have to admit that even though smart, we have fallen again for Big Brothers B.S.

I think what ever works for each patient should be legal. Dr. and patients know what it takes too stop enough pain for a person to have a life besides staying in bed and having no quality of life. Old or young nobody should have to exist in horrific pain 24/7. Most take medication for their pain and don’t consider taking it as a drug high. I never got high from my medication it just helped with the pain, it never even stopped the pain but it helped.

Lori J Esposito

Im another satisfied monkey I was on so many opiods I hated being in my own body, never mind dealing w the pain. So I moved to a legal State, started medical marijauana an CBD oil; I can now say Im off 5 medications, an down to 1 pain pill a day !!
There is an alternative to opiods an it doesnt mean you have to smoke alot, all kinds of options! Look into CBD also…it all works together to keep us healthier an happy!

Am I perhaps being too unkind to the article, and therewith those who wrote it?? I think not! For the simple fact of the matter is that unless you are actually LIVING with severe chronic, totally debilitating, pain you really can have no idea of what such misery actually entails, which means, at least to me, that you have no right to be making up policies for, or, frankly, even merely advising, those person who ARE in such intractable pain about what they can and cannot do to get some relief! And that goes double and triple for all the erstwhile used car salesmen who, despite, or because?, of their staggering ignorance about most everything, somehow got themselves elected to the state legislature, and who, upon attaining such a dubious disticntion, inexpicably deem themselves competent enough about matters medical to proscribe all physicians, — even those who, like my own, have 50 years experience treating chronic pain patients safely and compassionately, — from prescribing ANY form of opioid medicine to their patients! Of course this is always done in the pious name of the drug panic de jour, which just now seems to be the “opioid crisis,” — just as before it was the “meth” crisis, and before that the “crack” crisis, “ice,” or “ecstacy,” or “LSD” or “cocaine,” or “marijuana,” or the first “opium” crisis — which in fact is an injected heroin/fentanyl overdose problem which has nothing whatsoever to do, — as several studies attest with hard data, — with the prescribing of pain meds. In fact, at the risk of preaching to the choir here, during the last five years of this latest drug hysteria prescriptions for opioid pain meds have dropped a truly criminal 70+%, while drug injection deaths have quadrupled. So much for the tired theory that pain pills are a “gateway” to shooting up smack!! [Did you know, btw, that a full 98% of all heroin addicts were first addicted to , — and I mean intensely craved and just couldn’t go without — their mother’s milk?]

Here’s another, perhaps more poignant way of making the same point I made in my last comment. Just allow me to change a few words in the article’s main thesis; ““These findings suggest that using opioids and Tylenol together could offer a safe way to cut opioid dosage among patients suffering from pain, and may reduce their risk of opioid addiction.” In fact that “solution” in search of a problem would actually be much better than what most of us have been offerred by this gratutitously cruel police state we live in, since at least then we would still be receiving at least SOME dose of opioid pain medicine, however insufficient to go along with the nearly useless Tylenol that is all we are allowed now under the status quo!!

Why I can almost hear the doctor’s rejoinder to the implementation of such a malicious “opioid reduction” policy now; “What, you’re still in pain? — said with a scowl that implies that you must therefore be something of a very bad boy or girl! — Well, there’s nothing else I can safely do for you, except, I suppose, bump you up to the extra-strength 500mg. dose of Tylenol from the 325mg. dose you’re now on …. but just remember, only four grams per day total, because more acetaminophen than that could well cause liver failure and kill you!” — while, of course, the opioid med you should be on is NOT known to have such long term debilitarting effects.

So then, in this decidedly opiodophobic country the regnant principle for opioids is “safety unto screaming misery and death,” — as if a victim needs to be protected against anything in this world a third as much as against chronic horrific pain! — while for Tylenol, and all the other equally dangerous, and largely ineffective, over-the-counter pain meds, the guiding rule seems to be; “well, of course, there’s some probability of permanent damage involved, but, hey, who ever said life is without some risks?”

Terry

I agree with Dr. William Fusfield.I tried some edible marijuana and I was so stoned all I could do was go to sleep, it was horrible, and it did nothing for my pain. Not to mention, how are you going to pass a drug screen? Granted, I never had a high tolerance for marijuana and as a teenager I probably smoked it 5 times total and I didn’t like anything about it, maybe it’s my low tolerance, who knows? But trying to get your pain doctor to help you get a medical marijuana card? It ain’t gonna happen, not mine anyway. The only thing that will help is if the CDC came out with new guidelines for chronic pain patients and leave it up to the pain management doctors to prescribe what we need. It’s all very hopeless to me, my life is ruined, I’m in horrible pain 24 hours a day and that’s just the way it is. Side note: Who even cares if chronic pain patients get addicted to opioids? See my point? CHRONIC pain patients, CHRONIC. I personally don’t care if I get hooked on pain pills, my body will never get better so who cares? Very wrong and frustrating. Hang in there everyone, God bless you all.

susan

Never would of thought they’d have a survey on this. Don’t the powers that be have a stupid thought. Everyone experience is so different. Where is the money coming from? The tax payers? Yet we suffer..Thank-you

Michael Boyett

Last year I was able to taper and stop using opiates by using marijuana during the final months. Of course, as all pain patients know, I was unable to use marijuana during most of my self directed taper due to drug testing all clinics must conduct. Now I use cannabis to help with the worst pain periods, but as many also know, it is not as effective as the opiates I used to take, but I no longer have to deal with being treated as a drug addict or any of the negatives that come with opiate treatment.

I was lucky to find a good doctor who worked with me and allowed me to set a taper schedule that was slow enough that I did not feel any withdrawal symptoms. It took about a year with about a 10% drop each month – at first I put myself ahead of the schedule so I had a built in cushion in case I had any difficulty. It turned out I did not experience any problems and I was able to use the amount left to finish my taper using cannabis without worrying about drug testing.

Of course the elephant in the room is I now have to live with pain, but it has been liberating to not have to deal with the “medical” establishment and government watchdogs “concerned” I’m going to overdose after 15 years of being a stable patient who never ran out early or exhibited any drug seeking behaviors. I know some of my pain comrades are unable to live without the relief these medicines provide, but for the rest of us, I can assure you that it is possible to live without them – and give the finger to the do-gooders.

Yes I am fortunate to live in a state where I can use marijuana legally. I think my attitude made all the difference. I am free. That does not mean I’m happy about it or that I will no longer defend your right to find relief in whatever form that takes, just that I personally have found a different path. I force myself to go out and use my mind to ignore the nerve pain symptoms that will always be with me. Good luck to all of you searching for your own solutions

Larry F

The only result mentioned here is one of less negative side effects. Nowhere do you state whether the marijuana was adjunct therapy to some existing trial dose of morphine, or that the animal, already on morphine, was able to have that dose lowered when marijuana was added to the mix. So where is this tie-in to combined therapy reducing opiod dosage levels? It’s definitely not anywhere in this article.

Thomas Wayne Kidd

People are just grabbing for straws like the drowning person. I refuse to use weed. It does not work. It has dumbed down people for decades. Anything to keep from prescribing opioids that have worked for centuries. And the death toll will continue. Insanity continues.

Walter Strickland

Also ,are there any real DOCTORS in this group making all these insane decisions for OUR OWN GOOD ???

Walter Strickland

I will have to agree with Terri and DOCTOR William FUsfield on this subject.It’s getting insane.We are not animals, we are human beings with legitimate conditions that cause constant chronic pain.If I get cut off the medications I am in need of to survive my condition ,mark my words, I WOULD RATHER BE DEAD than have to go through that agaony I am hearing every day for the rest of my life with no releif to be found / except of course I can become a criminal and go the the streets and buy what ever I can get from the people who are fueling the problem and they should be the targets not law abiding people .Uncle Sam do you even want to understand that ???

Vincent Morraele

This will not work in a work environment at all! Though it may help some. No employer will hire a person taking this type of medication you wouldn’t get the job but people in bed or that don’t drive ect it probley will help but what’s the cost and would insurance companies pay for it.

Lisa Hess

From personal experience for myself and others that I know who are on the State Medical Marijuana programs, I have found what works for some, does not for all. And, on top of that, as far as I know, all states that have legal Medical Marijuana Programs, the patient is only allowed to be either on Opioids or the MM Program but cannot be on both. Years ago it was suggested I try the MM because my body’s damage and pain levels are so severe with head to toe pain every day nothing was helping even when taking 255MME before the tapering began. MM did nothing to help with my pain, whereas I know many people who didn’t want to take opioids and were weaning down while on the program and have had great success with Medical Marijuana and no longer need to take Opioids. Back to me, when the CDC mandates came down the pipeline with every taper I would retry every strain I had from over the 4 years experimenting with the Medical Marijuana for a few more months, I found that when I was on the high dose of Opioids the MM didn’t help at all and it was suggested from an expert in the Medical Marijuana field of study that he believed it was due to the high tolerance from the high dose of Opioids I was taking. Now I am at less than 65 MME and if I have pain levels of 5 or less (which is extremely rare) only 2 strains out of over the 25 different strains that I’ve collected over the years have worked. At my last taper, my pain is so severe nothing works. So now I wait for the government to stop it’s ridiculous 90MME mandates so my pain management doctor can bring my medications back up so I can have some quality of life. So, on a human experiment, it does work for some, but tolerance I have discovered plays a huge role. I have been on Opioids for 13 years with no addiction problems, but I do depend on what I can now take, just to stop screaming for a couple of hours when pain levels are so high.

Rebecca Hollingsworth

Ok well I guess I’m a monkey now. Over a year ago my pain management doctor gave me a medical marijuana card for my chronic insomnia. I was taking valium for years, but God forbid , now taking a benzo along with opiates is a no no. For years it was fine and I was fine. So now I smoke pot, excuse me, medical marijuana for Insomnia and sleep issues. Does it help? Not really, if I smoke my brains out with indica it may put me to sleep but it doesnt keep me asleep and not really into smoking every couple hrs during the night. That’s pointless. What it helps with is stress, anxiety, and muscle spasms. I have smoked for almost 40 years off and on and the one thing it DOESNT do is help me with my chronic pain. Maybe it helps others, but unfortunately not me. I was supposed to have 2 spinal fusions of all my lumbar vertebrae but the risks were half a page and the benefits were a single sentence with no guarantees. Ummm NO. I also have 3 herniated discs in my neck and 4 in my thoracic spine. I’m not a stoner or a pothead I left that behind many years ago and have no desire to live the rest of my life in a stupor. Give me back my high dose opiods that worked for years allowing me to do the same. I would trade pot for valium in a heartbeat. Honestly half the time I forget to smoke it b4 bed anyway. I guess growing up in a different time with a different perspective on marijuana, as a social drug, its not a big deal. But one thing I know for sure is it is not a cure all. It is not the be all end all for chronic pain patients. Keep up the fight for our rights so we can LIVE not just exist in this world. Prayers for all as I, myself, have found my mind going to dark places when the pain becomes unbearable. And feeling so much anger knowing that just the same time last year, life was good.

Rosalind Rivera

This is just great! Advise chronic pain suffered to combine Marihuana with OPIODS. So if you can’t get a prescription for it, you can go ahead and get it from the street corner vendor!

JRL

This is basically my current protocol and what has worked best (after trying everything). CBD on its own did nothing for me, it is the THC from which I benefit most, combined with a low dose of oxycodone ER.

Terri James

First it was mice, now it’s monkeys. We are neither although I am beginning to feel like such because of all of this hogwash. (Let’s just throw some more animal names in while we’re at it!) I do wish they’d stop giving them our medicine and give it back to us! I’m not an addict to my medicine; chronic pain although is addicted to me. Extremely large difference here. Don’t you get sick and tired of listening to experimental this and experimental that although it will take time and of course other professionals don’t agree?! Most of us just trying to hold on as is. Good Lord all of the insanity that goes with this Injustice is enough to make anybody sick!

The main thesis here seems to be: “These findings suggest that using opioids and marijuana together could offer a safe way to cut opioid dosage among patients suffering from pain, and may reduce their risk of opioid addiction.”

I can, of course, speak only for myself on this matter, but, contrary to all the massive HYPE around these days about the alleged analgesic properties of cannabinoids, especially THC, I for one obtain NO useful pain relief from using such ersatz pain medications. Even when I upped the dose significantly all I experienced was a very intense marijuana high, which I, unlike many people, do not particularly enjoy, without any concommitant reduction in my pain. In fact, all things considered, I would say that I was made MORE not less aware of the pain I was in by using the so-called “medical” marijuana products.

My expereince may, of course, not be typical. But I still feel that the basic thrust of this article plays right into the hands of all the drug warriors out there who wish to force all of us chronic pain patients off the opioid meds we need to live somewhat normal lives and into one or another of the many “opioid reduction programs” or, worse still, “pain management” scams that are now virtually obligatory for anyone seeking effective pain treatment, — which by the way is a basic human right under the UDHR! — including here in PA, where I myself, like tens of thousands of others, have been cut off my needed pain meds for almost a two years now thanks largely to the completely counterproductive, and outright dangerous, state legislation which now prevents physicians from prescribing even Schedule III opioids to their chronic pain patients, all in the ludicrous, and thoroughly disingenuous, belief that doing so will somehow reduce the nearly completely unrelated increase in injected heroin overdoses.

This article plays right into false assumption that opioid pain meds are a HUGE problem and must be “cut.” That’s a lie!

Kristen

This may be all well and good for some but I do get tested monthly and that being said If Marijuana ,alcohol and many more on the list is found in UT than my contract states I will no longer be recieving any more scripts because that would be a violation of my contract.Not to mention the cost of MMJ as well.Not many can afford it especially those on very limited income.Also many people can’t tolerate MMJ for one reason or another.I rather not test the waters on this one,it’s bad enough my pain med keeps getting decreased and with the severity of my pain that was once upon a time managed very well is now under managed and I am spending less time living and more time in bed just exsisting!

Here is my story...

I agree with this completely! Marijuana is all that many would have to turn to illegally to not commit suicide or turn to heroin! We should have both if we want! It is not to say pick marijuana or opiates! I was cold turkey cut off my pain medication like so many others right in the middle of cancer recurrence with tumors visible. Pain is pain – no need to separate cancer patients from CPP & the so called guidelines have not protected many cancer patients especially with their details of which cancer patients it’s to protect! Add that I’m an addict in recovery, despite at the time I was 7.5 years clean (now 10.5 years) nor did I ever have a failed drug test! I not only have cancer but also have many other pain related problems many which stem from chemo/radiation, here are “most” of them: an autoimmune disease that attacks the central nervous system effecting the heart & more, multi level herniated discs with arthritis & bone spurs w/ 54 degree scoliosis, IBS, Chronic Migraines variant-intractable, Neuropathy, Arthritis, Stomach Ulcers, Chronic Pain Syndrome, Clinical depression, 18 Shingle Outbreaks since 2010, Septic Shock & post Septic Shock which can very painful, Liver Enlargement with bile duct dilation which recur, Internal Bleeding “arteriovenous malformation” & can take no NSAIDS due to it. Also, due to my liver, I restrict Tylenol leaving me nothing! The doctors took my Dilaudid. I tried suffering for over a year & a half even with hospice home health overseeing me the doctor scared to approve palliative care for hospice who recommended it! Marijuana in 7wks confirmed w/MRI two metastatic spots were gone. I “know” it would work great to take medical grade marijuana with opiates. What someone else does should be between them & their doctor. The lack of testing on marijuana is the DEA’s fault! Re the study ‘addiction risk’ addicts are not all the same. Despite it even addicts or in recovery will need pain medicine like me with cancer or in pain.

Virginia

Well, this here monkey can hereby attest that this in fact is true. That combining opioids with marijuana does in fact work to help with reducing opioid use for the pain sufferer, and does not in fact cause any cognitive impairment. Especially when said monkey has been forced to reduce opioids, and has been also forced to find other ways to fight pain. Oh, and does also help with reducing the pain, almost, almost, as much as the proper amount of previous dosage of morphine. The other factor being that vaping nicotine along with the morphine and marijuana helps with couch lock and eating entire months supply of food in a fort night.:-)

Gary Raymond

Is this true? There is no marijuana abuse epidemic? Let’s add cocaine to the cocktail because there is no cocaine abuse epidemic either. The chaser could be meth. Mix it all in alcohol and suck it up in syringes provided by needle exchange programs. Lacing drugs is exactly what started this witch hunt – ask Dr. Redfield’s son. Persecuting those in chronic pain and holding axes over doctors’ heads are not going to stop black market activity and terrorism. Fentanyl should be considered as dangerous as Sarin.

F.S.T.

I’m willing to try this out! Currently in my State, marijuana possession is illegal. But with time, the pendulum swings, and my best guess is that it’s swinging toward legalization for medical use.

If it provides pain relief similar to opioids, I’m all for it!